Extending and Improving the Quality of Life

Understanding the biological basis of senescence may allow us to delay or prevent the degenerative declines long accepted as an inevitable part of getting older.

Caloric restriction is the only proven method of extending and improving the quality of human life discovered to date.

Resveratrol is a very promising candidate as it activates a gene called SIRT1 in humans, which regulates sirtuin proteins, which in turn “promote an ultra-protective “maintenance mode,” one that shields against the biochemical deterioration that increases the chance of disease over time. So it’s no accident that they play a role in controlling energy metabolism, endurance, and even the ability to resist cancer.”

In fact, caloric restriction works because “environmental stress, like calorie restriction, is what sends sirtuins into overdrive.”

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~ by notrous on April 30, 2009.

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